Cow's Milk Protein Allergy Symptom: Anaphylactic shock.

Anaphylaxis is considered a life-threatening generalized or systemic allergic (or hypersensitivity) reaction with sudden onset (minutes to a few hours).1 Many different definitions exist but most include similar details.  

It is suggested that increased awareness of anaphylaxis is needed among healthcare professionals, patients, caregivers and the public to ensure optimal treatments are achieved.1

The prevalence of the various causes of anaphylaxis are age-dependent and vary geographically.2 Although the fatality rate due to anaphylaxis remains low3 the frequency of hospitalizations due to food and drug-induced anaphylaxis has increased in recent years.4


in Infants?

In Europe, food-induced anaphylaxis in children is typically from peanut, hazelnut, milk, and egg; and in adults, wheat, celery, and shellfish.5,6 Venom-induced anaphylaxis is typically caused by wasps and bees.2

Could It Be a
Symptom of
Cow’s Milk
Protein Allergy?

Anaphylactic reactions commonly occur in the home setting (48%) and it’s been reported that food is the most common trigger (85% of cases).7 Of these foods, cow’s milk, peanut and tree nuts are among the most common causes of food-induced anaphylaxis in children.8,9

In one study they reported that cow’s milk accounted for 21% of 39 fatalities in children less than 16 years of age.4 It has also been identified in several reports of food-induced fatalities in infants.10

Note: infants or children who have had an anaphylactic reaction should always be seen by an allergy specialist.

Overview of Symptoms

Respiratory icon


Up to 30% of affected infants with CMPA have respiratory symptoms15,20

Anaphylaxis icon


Anaphylactic shock is a severe, immediate, allergic reaction, which can affect many organ/systems

Skin icon


Up to 75% of infants with CMPA can have skin-related symptoms21

General Symptoms icon


Inconsolable crying is very common in infants with CMPA associated with sleeping problems and food refusal